Best Chemical Resistant Gloves in 2025

The Best Chemical Resistant Gloves

When working in industries that involve hazardous chemicals, ensuring that your hands are protected is crucial. The best chemical resistant gloves can prevent injuries, skin irritation, and long-term health effects caused by chemical exposure. While there are many options on the market, not all are created equal. In this blog, we’ll explore which ones combine protection, performance, and comfort to make them the best chemical resistant gloves for a variety of applications.

Below is a list of the top five styles from our collection of chemical resistant work gloves, as well as a brief section on the best disposable gloves for chemicals. Let’s dive into the features, unique qualities, and best uses of each pair.

1. Showa Atlas 620 Gloves – Flexible Chemical Protection

Showa Atlas 620 Vinylove Gloves

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Showa Atlas 620 Vinylove Gloves are double-dipped PVC gloves designed for protection against oils, chemicals, acids, and solvents. Their seamless cotton liner provides comfort while their abrasion-resistant PVC coating offers superior grip in slippery conditions.

Features:

  • Acid and chemical-resistant protection
  • Rough grip for improved handling
  • Water-resistant and abrasion-resistant
  • 12-inch gauntlet cuffs for wrist and forearm protection
  • Ergonomic design to reduce hand fatigue

Best For: Chemical spraying, agriculture, painting, and coating preparation tasks that require both flexibility and durable chemical protection.

Cold-Weather Version: For those in need of cold weather work gloves, try the Showa Atlas 460 Cold-Resistant Vinylove Gloves. Built to stay flexible in temperatures as low as -4°F/-20°C, they are among the best chemical gloves for cold storage and winter work.

2. Showa Atlas 660 Vinylove Gloves – Superior Chemical Protection and Grip

Showa Atlas 660 Vinylove Gloves

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Showa Atlas 660 Vinylove Gloves provide ultimate protection with a triple-dipped PVC coating for enhanced resistance to oils, chemicals, acids, and solvents. These gloves are designed for durability, comfort, and precision in high-chemical environments.

Features:

  • Triple-dipped PVC coating for maximum protection
  • Seamless cotton liner for comfort and odor prevention
  • Rough grip for better handling in greasy or damp conditions
  • Extended cuffs for forearm protection
  • Machine washable for easy maintenance
  • Ergonomic design to reduce hand fatigue

Best For: Fishermen, fuel transporters, and maintenance workers. These gloves excel in wet, slippery environments and tasks like chemical spraying, coating preparation, and mining.

3. PIP Assurance 56-586CR PolyKor 14″ Nitrile Gloves – Protection for Chemicals and Cuts

PIP Assurance 56-586CR PolyKor 14" Nitrile Cut Resistant Chemical Gloves

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PIP Assurance 56-586CR PolyKor 14″ Nitrile Cut Resistant Chemical Gloves are some of the best chemical resistant gloves that offer cut resistance. With a PolyKor® blended liner and microfinish nitrile coating, these gloves offer excellent dexterity, ANSI Cut Level A4 protection, and are designed for high-performance in various environments.

Features:

  • Nitrile coating for superior grip in wet, oily, and dry conditions
  • PolyKor® blended liner for cut resistance, comfort, and flexibility
  • MicroFinish coating for liquid dispensing and protection against permeation
  • Puncture and abrasion resistance for added durability

Best For: Glass cutting, sheet metal handling, and general duty tasks. These gloves offer chemical protection and cut resistance for workers in construction, maintenance, and more.

4. PIP G-Tek 16-D622 Seamless Knit PolyKor Blended Polyurethane Coated Gloves – Enhanced Dexterity for Precision Tasks

PIP G-Tek 16-D622 Polyurethane Coated Gloves

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PIP G-Tek 16-D622 Seamless Knit PolyKor Blended Polyurethane Coated Gloves provide cut resistance, abrasion resistance, and dexterity. These gloves feature a PolyKor blended yarn for protection against mechanical hazards and a polyurethane coating for superior grip and durability.

Features:

  • Seamless knit construction for comfort and breathability
  • PolyKor blended shell for cut resistance and flexibility (Cut Level A2)
  • Polyurethane coating for abrasion resistance, puncture resistance, and dry grip
  • Fair grip in wet conditions, with liquids not absorbing into the coating
  • Knit wrist to prevent dirt and debris
  • Color-coded hems for size identification
  • Washable, resistant to chemicals, water, and UV light

Best For: Electronics assembly, glass cutting, metal handling, and food processing. These are the best chemical gloves for precision for delicate tasks.

5. Vanguard 11 Mil Unlined Nitrile Gloves –  Protection Against Heavy-Duty Chemicals

Vanguard 11 Mil Unlined Chemical Resistant Nitrile Gloves

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Vanguard 11 Mil Unlined Chemical Resistant Nitrile Gloves provide protection against grease, fats, and harsh cleaning solutions while offering exceptional dexterity and reducing product contamination.

Features:

  • 11-mil thickness for durability against heavy-duty chemicals and oils
  • Unlined design for maximum dexterity
  • Raised diamond texture for a non-slip grip in dry, wet, and oily conditions
  • Puncture, abrasion, and cut-resistant nitrile
  • 13-inch length with a straight cuff for forearm protection

Best For: Janitorial, food service, food processing, and chemical processing tasks. These gloves offer both chemical protection and a superior grip for cleaning and industrial work.

Best Disposable Gloves for Chemicals

Nitrile Disposable Gloves

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While reusable chemical resistant gloves provide long-term protection for various industrial tasks, there are also situations where disposable gloves are needed, especially for short-term tasks or quick chemical cleanups.

The best disposable gloves for chemicals are made of nitrile material. Nitrile disposable gloves provide a flexible, chemical-resistant barrier, perfect for tasks where you need short-term protection without sacrificing dexterity. They also offer superior puncture resistance, making them a go-to option for medical, cleaning, and laboratory environments. Check out our blog on the Best Nitrile Gloves for specific recommendations.

Conclusion: Choosing the Best Chemical Resistant Gloves

When it comes to selecting the best chemical resistant gloves, the right pair depends on the specific tasks you’ll be performing. The Showa Atlas 620 and 660 gloves are ideal for general use. For more demanding tasks, the PIP Assurance Gloves provide the cut resistance and chemical protection needed for demanding industrial environments, while the PIP G-Tek 16-D622 Gloves offer a balance of dexterity and chemical resistance for precision tasks. Lastly, the Vanguard 11 Mil Gloves provide excellent protection against harsh chemicals like grease and fats for cleaning applications and more. These five gloves offer a range of protection suited to a variety applications, which is why we consider them the best chemical resistant gloves on the market.

For more information on protective gear, visit our Chemical Resistant Safety Wear blog post, which covers general safety wear and offers additional product insights. Check out our full chemical resistant glove collection and order online for free shipping on orders over $80 and volume discounts. Contact a product expert to learn more about choosing the best chemical gloves for your business. Don’t wait — protect your hands today!